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Shah Rukh Khan's Red Chillies Responds to Sameer Wankhede, Says Satire and Fiction Can Co-exist_我的网站

A |     Shah Rukh Khan's Red Chillies Entertainment has responded to Sameer Wankhede's defamation suit over a scene in Aryan Khan's show The Ba***ds of Bollywood. They claimed that while the show depicts an overzealous officer, it does not reference the Cordelia cruise case. IRS officer Sameer Wankhede pleaded in the Delhi High Court seeking an interim injunction on Aryan Khan's series. Responding to Wankhede's claims, senior advocate Neeraj Kishan Kaul, appearing for Red Chillies said that satire and fiction can co-exist.     "Can satire and fiction co-exist? There is no law that it cannot co-exist. I may be partly inspired by real persons and stories, yet there can be disclaimers, no problem with two existing together. Where is the ill-will or malice? This is about a success story in a Bollywood party. We are not looking at people who are sensitive; hurt is not ground for malice. Can you pick a stray instance, a passage here or there? The series is about 20 different issues. We do not show a documentary on the Cordelia cruise incident. I am inspired by overzealous officers. That is far from saying that this is the Cordelia cruise story."          For the uninitiated, in 2021, Wankhede who was with the Narcotics Control Bureau, arrested Aryan Khan from the Cordellia cruise over a drugs case. However, Khan's name was cleared later, and he was released from jail. In his show, there is a scene where an inspector from a fictional anti-narcotics agency arrests an actor over a false drug case. Wankhede argued that the officer shown in the show resembles him and urged that the scene should be removed from the show.     Taking a dig at Wankhede, advocate Kaul also argued that Wankhede loves giving interviews to the media and spoke about the issues after the show released.          He continued, "You cannot say that the person depicting ills in Bollywood cannot show overzealous officers. I cannot be responsible for what other people say… I am fully entitled to depict issues ailing Bollywood. Even if I am to project someone, a public official cannot be that thin-skinned. Even if I portray you unjustly it is still not a case. Every scene in this show is exaggerated. I am not ridiculing him or the emblem. I am talking about officials who have lofty idea."     Wankhede sued Red Chillies, Netflix and Aryan Khan for defamation.     The next hearing on this case is on Thursday.     Also Read: ’Not Without Bias’- Delhi High Court Pulls Up Red Chillies Over Sameer Wankhede’s Defamation Case。    我们对抗癌症--乃至所有疾病--的最大武器是我们的免疫系统，但即使它有时也需要一个帮手。

B | 免疫疗法提供了这种帮助，其中一种方法即所谓的免疫检查点抑制剂。这些药物能有效地解除免疫反应的自然刹车，从而使其能更长时间地跟癌症作斗争。尽管到目前为止这些药物看起来很有希望，但它们对一开始就没有什么免疫活动的“冷 ”肿瘤不起作用。因此，另一种类型的药物被称为STING激动剂，旨在将这些冷肿瘤激发为热肿瘤，从而使其更容易接受免疫疗法。但这些药物也有其缺点--即很难将它们瞄准癌细胞。而这正是这项新研究的意义所在。

C | 来自耶鲁大学和URI的研究人员使用了一种叫做低pH插入肽(pHLIP)的分子来引导药物到它需要去的地方。pHLIP被吸引到酸性环境中，就像癌症在自身周围形成的那种环境一样，非常方便。该研究的论文共同作者Donald Engelman说道：“当pHLIP遇到具有中性pH值的细胞膜时，它将短暂地坐在表面，然后拉走。但如果它处于酸性环境中，那么该肽就会折叠成一个螺旋，穿过细胞膜并停留在那里。”该团队将pHLIP跟STING激动剂结合起来，从而使前者将后者带到癌细胞并帮助它们在内部开始工作。在小鼠身上的测试证明是有希望的--研究人员给20只患有小结肠肿瘤的小鼠注射了pHLIP-STING，发现在一次注射后，18只小鼠的肿瘤在几天内完全消失了。

D | 在另一组有较大肿瘤的小鼠中，10只小鼠中有7只看到它们的肿瘤完全消失。相比之下，另一组10只小鼠只接受了STING，它们没有pHLIP的指导。所有10只小鼠的肿瘤生长都略有减缓，但肿瘤仍然存在。这种治疗甚至似乎具有持久的效果。研究小组将新的癌细胞注射到已无肿瘤的小鼠体内，结果60天后没有新的肿瘤出现，这表明免疫记忆已经形成。虽然这项技术听起来很有希望，但通常的注意事项也是适用的--动物试验的结果并不总是能延续到人类身上。在任何基于pHLIP-STING的潜在治疗方法能够找到用途之前还需要做更多的工作。

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Published on:18:44:19